NIH
House and Senate Appropriations Committees Approve FY 2016 Labor-HHS Bills
The Appropriations Committees in the House and Senate advanced their respective fiscal year (FY) 2016 bills for Labor, Health and Human Services, Education, and Related Agencies (Labor-HHS). The House passed its version on June 24 (see COSSA’s preliminary analysis of the bill), and the Senate on June 25. Both bills would provide sizable increases for the National Institutes of Health (NIH), with a larger increase coming from the Senate’s bill. The House bill proposes to completely eliminate the Agency for Healthcare Research and Quality (AHRQ) but maintains strong funding for the Centers for Disease Control and Prevention (CDC), while the…
OBSSR Marks 20th Anniversary at NIH, on Capitol Hill
The National Institutes of Health (NIH) Office of Behavioral and Social Sciences Research (OBSSR) marked its 20th anniversary with a three-day celebration on June 23-25 on the NIH Bethesda campus and Capitol Hill. The celebration began with the 8th Matilda White Riley Award and Lecture in Behavioral and Social Sciences on June 23. The award is given in recognition of an outstanding behavioral or social scientist whose research has contributed to both the deepening of knowledge and its application in a manner that furthers NIH’s mission of improving health. This year the award went to Kevin Volpp and Jeanne Brooks-Gunn.
NIH Issues Notice on Enhancing Reproducibility
On June 9, the National Institutes of Health (NIH) Office of Extramural Research (OER) issued a Notice (NOT-OD-15-103) in an effort to clarify and revise application instructions and review criteria “to enhance reproducibility of research findings through increased scientific rigor and transparency.” The release of the Notice is to raise awareness and begin “culture shifts in the scientific community.” In a June 9 blog post, Sally Rockey, NIH Deputy Director for Extramural Research, and Larry Tabak, Principal Deputy Director of NIH, explained, “These changes will prompt applicants and reviewers to consider issues, which—if ignored—may impede the transparency needed to reproduce key…
Members of Congress Address NIH Precision Medicine Working Group Workshop on Digital Health Data and Research Cohort Design
Senator Lamar Alexander (R-TN) and Representative Marsha Blackburn (R-TN) addressed a special session of the National Institutes of Health (NIH) Advisory Council to the Director (ACD) Precision Medicine Initiative Working Group at the Public Workshop, Digital Health Data and Research Cohort Design, on the campus of Vanderbilt University on May 28-29. The workshop is part of series by the ACD Working Group and builds on the April 28-29 workshop held on the NIH campus that focused on the development and implementation of a large national cohort, as well as identification of the unique scientific questions and opportunities of using such…
NIH Minority Health Institute Moves Ahead on Science Visioning of Health Disparities
At the June 9 meeting of National Advisory Council on Minority Health and Health Disparities (NACMHD), outgoing Acting Director Yvonne Maddox updated the Council on the Institute’s Science Visioning process for health disparities research. NIH Deputy Director Larry Tabak will serve as the Institute’s Acting Director until newly appointed director Eliseo Perez-Stable’s arrival in September. To initiate the process, the Institute released a request for information in April (see Update, May 4, 2015). Maddox reported that a trans-NIH Science Vision Advisory Group had been appointed and working groups are being established. The working groups will hold discussion forums around areas…
NIH Requests Comment on Precision Medicine Cohort, Strategies to Address Community Engagement and Health Disparities
The National Institutes of Health (NIH) is seeking feedback (NOT-OD-15-107) to help it in creating a national research cohort of one million or more Americans as part of the President’s proposed Precision Medicine Initiative (PMI) (see Update, May 19, 2015). The agency is specifically interested in feedback relating to the development and implementation of effective community engagement strategies for the cohort, and the ability to conduct transformative research to address health disparities. The aim is to assemble a “cohort reflective of the rich diversity of the U.S. population.”
NIMHD: Advancing Health Disparities Interventions Through Community-Based Participatory Research
Research supported by the National Institutes of Health (NIH) has resulted in an increasing growth in knowledge of the complexity of the interactive factors influencing health across the life course. There is extensive research evidence that report poorer health outcomes for socially disadvantaged populations, including low-income and racial and ethnic groups. Many community health promotion and disease prevention programs fail for various reasons that include the lack of a participatory approach or cultural sensitivity, despite the recommendation for tailored and multilevel interventions.
NIH: The Health of Sexual and Gender Minority Populations
The National Institutes of Health (NIH) has issued a funding opportunity announcement (FOA) focused on sexual and gender minority (SGM) populations, including lesbian, gay, bisexual, transgender, and intersex populations. Participating institutes and offices include: Cancer, Alcohol Abuse and Alcoholism, Allergy and Infectious Diseases, Deafness and other Communication Disorders, Dental and Craniofacial, Mental Health, Minority Health and Health Disparities, and the Office of Behavioral and Social Science Research.
NIMHD: Building Population Health Research Capacity in the U.S. Affiliated Pacific Islands
The United States-Affiliated Pacific Islands (USAPI) consist of the U.S. territories of American Samoa, Guam, the Commonwealth of the Northern Mariana Islands, the Federated States of Micronesia, Republic of the Marshall Islands, and Republic of Palau. The U.S. is responsible for the essential operations, health, education, and defense for these jurisdictions. The residents of these jurisdictions are considered to be a U.S. health disparity population. The National Institutes of Health (NIH), however, acknowledges that this geographic region has received very little NIH support to conduct health and health disparities research.
Analysis of the Draft 21st Century Cures Act
On May 14, the House Energy and Commerce Health Subcommittee approved by voice vote its discussion draft of the 21st Century Cures Act. An amendment to an earlier discussion draft was introduced by full committee Chairman Fred Upton (R-MI), Rep. Diana DeGette (D-CO), Health Subcommittee Chairman Joe Pitts (R-PA), full committee Ranking Member Frank Pallone, Jr. (D-NJ), and Health Subcommittee Ranking Member Gene Green (D-TX). The bipartisan amendment incorporated federal agency and scientific community feedback to a draft bill the preceding day. The legislation is scheduled to be considered by the full Energy and Commerce Committee the week of May…
NIH: AIDS Research Center/Developmental Research Centers on Mental Health and HIV/AIDS
The Division of AIDS Research (DAR) within the National Institute of Mental Health (NIMH) at the National Institutes of Health (NIH) is seeking applications for Center Core grants to support an HIV/AIDS Research Center (ARC) (PAR-15-197) and applications to support Developmental AIDS Research Centers (D-ARC) (PAR-15-196). ARC supports innovative, interdisciplinary research in the areas of basic research, neuro-AIDS, behavioral and social, integrated biobehavioral, clinical, translational, and implementation science. D-ARC provides infrastructure support that facilitates the development of high impact science in HIV/AIDS and mental health that is relevant to the NIMH mission. NIMH’s intent is to support research that addresses…
PCAST Hears Interim Report on Precision Medicine Initiative
On May 15, the President’s Council of Advisors on Science and Technology (PCAST) received an interim report on the President’s proposed Precision Medicine Initiative (PMI). Opening the meeting, PCAST co-chair and director of the White House Office of Science and Technology Policy (OSTP) John Holdren discussed the ongoing budget process and the challenges associated with the FY 2016 budget. Despite these challenges, Holdren noted, there are a number of exciting initiatives in progress, including the Precision Medicine Initiative.
NIH Appears Before Senate Appropriations Subcommittee
On April 30, National Institutes of Health (NIH) director Francis Collins made his annual appearance before the Senate Appropriations Subcommittee on Labor, Health and Human Services, Education, and Related Agencies (Labor-HHS) to discuss the President’s proposed FY 2016 budget request for the agency. The NIH director was accompanied by several institute directors: Anthony Fauci, National Institute of Allergy and Infectious Diseases (NIAID), Douglas Lowy, National Cancer Institute (NCI), Gary Gibbons, National Heart, Lung, and Blood Institute (NHLBI), Jon Lorsch, National Institute of General Medical Sciences (NIGMS), and Tom Insel, National Institute of Mental Health (NIMH). Subcommittee Chairman Roy Blunt (R-MO)…
House Energy and Commerce Committee Releases Second Version of 21st Century Cures Draft
On April 29, the House Energy and Commerce Subcommittee on Oversight and Investigations released the second iteration of the Committee’s 21st Century Cures bill (see Update, February 24, 2015). The latest draft is a collaborative effort by Chairman Fred Upton (R-MI), Ranking Member Diana DeGette (D-CO), Energy and Commerce full committee Ranking Member Frank Pallone, Jr. (D-NJ), Health Subcommittee Chairman Joe Pitts (R-PA), and Health Subcommittee Ranking Member Gene Green (D-TX). The new version of the discussion draft would authorize the National Institutes of Health (NIH) for three years (FY 2016 through FY 2018), and increase its funding level by…
Eliseo J. Pérez-Stable Named Director of the National Institute on Minority Health and Health Disparities
On April 28, National Institutes of Health (NIH) Director Francis S. Collins announced the selection of Eliseo J. Pérez-Stable, M.D. as Director of the National Institute on Minority Health and Health Disparities (NIMHD). He is expected to join NIH in September. Currently at the University of California San Francisco (UCSF), Pérez-Stable is a professor of medicine, chief of the Division of General Internal Medicine, and director of the Center for Aging in Diverse Communities. He is also director of the UCSF Medical Effectiveness Research Center for Diverse Populations, which is addressing issues for African Americans, Asians, and Latinos in the…
NIH: NIMHD Seeking Input for Health Disparities Science Vision
The National Institute on Minority Health and Health Disparities (NIMHD) within the National Institutes of Health (NIH) serves as the focal point for the agency’s conduct of research, research training, capacity-building, and outreach dissemination of minority health and health disparities. NIMHD recently initiated a scientific planning process in collaboration with the NIH institutes and centers designed to define a vision that will guide the development of “the science of health disparities research for the next decade and identify key research areas that should be given high priority because knowledge in those areas might inform translational efforts that could have a…
NIH: Input Sought on Precision Medicine Cohort
The National Institutes of Health (NIH) is seeking feedback from the scientific community via a Request for Information (RFI): NIH Precision Medicine Cohort (NOT-OD-15-096) to guide it in creating a longitudinal cohort of one million or more Americans who have volunteered to participate in research as part of the President’s proposed Precision Medicine Initiative (PMI) (see Update, April 21, 2015). Specifically, the agency is seeking information on characteristics, purpose, or other overall aspects in the development and implementation of a large U.S. precision medicine cohort. As participants in PMI, individuals will be asked to give consent for extensive characterization of…
NIH: Collaborative Innovation Award, Clinical and Translational Science Award Program
The National Center for Advancing Translational Sciences (NCATS) within the National Institutes of Health (NIH) is inviting applications to stimulate innovative collaborative research in the NCATS Clinical and Translational Science Award (CTSA) consortium. Because translating biomedical discoveries into clinical applications is essential to improving health and at the same time a complex process with high costs and substantial failure rates, the CTSA hubs are designed to promote advances in translational research and training at participating medical research institutions. NCATS recently released a funding opportunity announcement (FOA), Collaborative Innovation Award, Clinical and Translational Science Award Program (PAR-15-172), to enable collaboration among…
NIH Appoints Working Group for Precision Medicine Initiative
In March, National Institutes of Health (NIH) director Francis Collins appointed a team of individuals to serve on the Advisory Committee to the NIH Director (ACD) Working Group on the Precision Medicine Initiative (PMI). The Working Group is expected to host public meetings to seek public input into the development of President Obama’s proposed Precision Medicine Initiative. This group will help the NIH define “what can be learned from a study of this scale and scope, what issues will need to be addressed and considered as part of the study design, and what success would look like five and ten…
RFI: Optimizing Funding Policies and Other Strategies to Improve the Impact and Sustainability of Biomedical Research
The National Institutes of Health (NIH) has issued a Request for Information (RFI), Optimizing Funding Policies and Other Strategies to Improve the Impact and Sustainability of Biomedical Research, soliciting input from the scientific community regarding the possible development of new policies and other strategies to improve the impact and sustainability of the NIH-funded biomedical research enterprise.